<p>One of the most promising and environmentally friendly areas of the synthesis of silver nanoparticles, exhibiting a wide range of biological activity, is the use of plant and fungal extracts. Using an aqueous extract of the mycelium of the <i>Trametes versicolor</i> strain, round silver nanoparticles with an average diameter of 11.34 ± 0.31&#xa0;nm and a zeta potential of − 20.1 were obtained. The biological activity of the obtained preparation was studied using a test strain of <i>E. coli</i>. The nanoparticle preparation exhibited pronounced antibacterial activity against the test strain of <i>E. coli</i>: the minimum inhibitory concentration of the preparation was 2.5&#xa0;μg/ml; the minimum bactericidal concentration was 5&#xa0;μg/ml. The fungistatic effect of AgNPs against the test strains of <i>Fusarium sporotrichioides</i> and <i>F. solani</i> was also demonstrated; the most pronounced effect was exhibited by the preparation with a concentration of 100&#xa0;μg/ml. The obtained results demonstrate the potential of using <i>Trametes versicolor</i> extracts to develop efficient methods for synthesizing small-sized AgNPs, which can be applied in the fields of medicine, biopharmaceuticals, and agriculture.</p> Graphical Abstract <p></p>

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Biosynthesis of Silver Nanoparticles Using the Basidiomycete Trametes versicolor

  • Nataliya Feldman,
  • Irina Gavryushina,
  • Elena Zinurova,
  • Sergey Orekhov,
  • Mikhail Zyankin,
  • Peter Gromovykh,
  • Sergey Lutsenko

摘要

One of the most promising and environmentally friendly areas of the synthesis of silver nanoparticles, exhibiting a wide range of biological activity, is the use of plant and fungal extracts. Using an aqueous extract of the mycelium of the Trametes versicolor strain, round silver nanoparticles with an average diameter of 11.34 ± 0.31 nm and a zeta potential of − 20.1 were obtained. The biological activity of the obtained preparation was studied using a test strain of E. coli. The nanoparticle preparation exhibited pronounced antibacterial activity against the test strain of E. coli: the minimum inhibitory concentration of the preparation was 2.5 μg/ml; the minimum bactericidal concentration was 5 μg/ml. The fungistatic effect of AgNPs against the test strains of Fusarium sporotrichioides and F. solani was also demonstrated; the most pronounced effect was exhibited by the preparation with a concentration of 100 μg/ml. The obtained results demonstrate the potential of using Trametes versicolor extracts to develop efficient methods for synthesizing small-sized AgNPs, which can be applied in the fields of medicine, biopharmaceuticals, and agriculture.

Graphical Abstract