<p>The emergence and advancement of nanotechnology have brought nanomaterials into close proximity with human life through applications such as water remediation, diagnostics, therapy, skin protection, catalysis, electronics, and more. Over the past two decades, researchers have extensively explored and commercialized the biomedical applications of nanoparticles. The amalgamation of nanotechnology with dermaceuticals has significantly improved the quality and effectiveness of cosmetic products. Their use in cosmetic products has improved efficacy by increasing penetration efficiency, enhancing UV protection ability, prolonging the effect, and improving appearance and fineness. Among several types of nanomaterials, biosynthesized ones have shown promising potential in cosmetic applications, and they can be used as UV blockers, anti-aging and moisturizing agents, anti-inflammatories, antioxidants, anticancer agents, and wound-healing materials in skin care products. Additionally, biomaterials provide an ancillary effect to nanomaterials, increasing the performance of cosmetic ingredients. The present review provides information on various nanomaterials synthesized using different biomaterials and their role in skin care applications. This review also discusses the economic viability and potential toxicity of nanoparticle-based cosmetic products. Finally, we address the challenges associated with biosynthesized nanomaterials in cosmetic and skin care products.</p> Graphical Abstract <p></p>