<p>True triaxial compression experiments were conducted on jointed rock with different Joint Roughness Coefficient (JRC, JRC = 4.78, 9.57, 14.74 and 19.47) or inclined angle (<i>α</i> = 30°, 45°, 60° and 90°) firstly. Then, the adaptive transform a Lagrangian solid element to Discrete Element Sphere particles (adaptive Solid to DES) method was employed to realize the true triaxial compression simulation on jointed rock with various JRC and <i>α</i>. The results show that: (1) The maximum equivalent stress and cracks are firstly concentrated at the joint asperities and develop into the rock matrix with increasing axial stress, resulting in joint-matrix coupled fracture mode. (2) The strength and peak strain of the jointed rock show a decreasing (30 ° ≤ <i>α</i> ≤ 60°) then increasing <i>α</i> = 90°) tendency as the <i>α</i> increased. Increasing JRC weaks the influence of <i>α</i> on strength but amplify on peak strain. (3) When the joint strike parallels to intermediate principal stress, the failure mode are matrix shear (<i>α</i> = 30°), matrix shear-joint sliding (<i>α</i> = 45°), joint sliding (<i>α</i> = 60°), to matrix shear failure (<i>α</i> = 90°), respectively. When the joint strike parallels to minor principal stress, the larger stress on the inclined side inhibits the influence of the joint, resulting in all jointed rock matrix shear fracture.</p>