Objective <p>To evaluate the effects of inferior turbinate lateralisation and duration of silicone nasal splint use on postoperative patient comfort and complications following septoplasty.</p> Materials and Methods <p>Fifty-eight patients underwent septoplasty alone, and seventy-seven underwent septoplasty with inferior turbinate lateralisation. Sixty-eight patients had a 3-day silicone nasal splint and sixty-seven patients had a 7-day silicone nasal splint after surgery. All patients completed the ‘Nasal Splint Survey’ after removal of the silicone nasal splints.</p> Results <p>No significant differences were observed in overall patient-reported comfort scores between the 3-day and 7-day silicone nasal splint groups. However, crusting and early bleeding were less frequent in the 7-day silicone nasal splint group. Inferior turbinate lateralisation was associated with a significantly higher rate of sneezing. Overall complication rates were lower in both the 7-day silicone nasal splint group and the lateralisation group. However, patient-reported discomfort tended to be higher in the 7-day silicone nasal splint group.</p> Conclusion <p>7-day silicone nasal splinting and inferior turbinate lateralisation are associated with reduced postoperative complication rates, but may reduce patient comfort. Splint duration should therefore be individualized based on surgical context and patient tolerance.</p>