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Background <p>Follicular Unit Extraction (FUE) is a standard technique for hair restoration. However, post-transplant graft survival and early regrowth can be compromised by ischemic injury and delayed vascularization. Platelet-rich plasma (PRP), rich in growth factors, may enhance graft survival and follicular growth.</p> Aim <p>To compare the efficacy of intraoperative PRP in FUE hair transplantation.</p> Methods <p>A prospective, randomized study was conducted on 60 male patients with androgenetic alopecia. Group A (<i>n</i> = 30) underwent FUE with PRP, and Group B (<i>n</i> = 30) underwent FUE without PRP.</p> Results <p>At 6 months, all PRP patients (100%) achieved ≥ 75% regrowth versus 40% in controls (<i>p</i> &lt; 0.000001). Hair density was significantly higher in the PRP group at 1 month (66.7% vs. 16.7%), 3 months (80% vs. 43.3%), and 6 months (100% vs. 40%). Mean hair shaft length at 6 months was greater with PRP (12.3&#xa0;mm vs. 8.4&#xa0;mm, <i>p</i> &lt; 0.0001). Scalp redness resolved faster (24 vs. 36 days, <i>p</i> &lt; 0.0001) and satisfaction scores were higher (8.4 vs. 7.1, <i>p</i> &lt; 0.0001).</p> Conclusion <p>Intraoperative PRP significantly improves graft survival, accelerates regrowth, promotes faster healing, and enhances patient satisfaction in FUE hair transplantation.</p>

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Efficacy of Intraoperative Platelet-Rich Plasma in Follicular Unit Extraction Hair Transplantation: A Prospective Study

  • 期刊论文

  • 发表日期：

    2026年3月4日

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  • Pawan V. Dawane,
  • VIJAY N. Rode,
  • Snehal M. Bharsakle,
  • Akash P. Kadam,
  • Gujan K. Hiware

摘要

Background

Follicular Unit Extraction (FUE) is a standard technique for hair restoration. However, post-transplant graft survival and early regrowth can be compromised by ischemic injury and delayed vascularization. Platelet-rich plasma (PRP), rich in growth factors, may enhance graft survival and follicular growth.

Aim

To compare the efficacy of intraoperative PRP in FUE hair transplantation.

Methods

A prospective, randomized study was conducted on 60 male patients with androgenetic alopecia. Group A (n = 30) underwent FUE with PRP, and Group B (n = 30) underwent FUE without PRP.

Results

At 6 months, all PRP patients (100%) achieved ≥ 75% regrowth versus 40% in controls (p < 0.000001). Hair density was significantly higher in the PRP group at 1 month (66.7% vs. 16.7%), 3 months (80% vs. 43.3%), and 6 months (100% vs. 40%). Mean hair shaft length at 6 months was greater with PRP (12.3 mm vs. 8.4 mm, p < 0.0001). Scalp redness resolved faster (24 vs. 36 days, p < 0.0001) and satisfaction scores were higher (8.4 vs. 7.1, p < 0.0001).

Conclusion

Intraoperative PRP significantly improves graft survival, accelerates regrowth, promotes faster healing, and enhances patient satisfaction in FUE hair transplantation.