Multidisciplinary Management of Aggressive Giant Cell Tumour of the Mandible Using Denosumab, Virtual Surgical Planning, and Patient-Specific Implants: A Case Report with Myasthenia Gravis Considerations
摘要
Introduction
This report describes the management of an aggressive mandibular giant cell tumour (GCT) in a 59-year-old male with comorbid myasthenia gravis (MG).
Case ReportA multidisciplinary approach incorporating neoadjuvant Denosumab, virtual surgical planning, and patient-specific implants enabled precise tumour resection and reconstruction while minimising anaesthesia-related risks.
Results and ConclusionThe use of advanced techniques significantly reduced surgical time and enhanced functional and aesthetic outcomes. This case highlights the feasibility and effectiveness of integrating modern chemotherapeutics and digital technologies in surgically managing complex maxillofacial tumours, particularly in patients with high perioperative risk due to systemic conditions like MG.