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<p>Clear cell odontogenic carcinoma is a very rare malignant tumor of the jaw. Diagnosis and treatment may be challenging as the tumor grows locally aggressive and infiltrative with possible metastatic spread, while the clinical presentation varies, and the definitive diagnosis can only be confirmed by immunohistopathology. The case of a 25-year-old male patient with clear cell odontogenic carcinoma of the mandible is presented. Therapeutic treatment included primary surgical resection with bilateral removal of cervical lymph nodes followed by a two-stage reconstruction approach. Continuous follow-up over 7.5&#xa0;years showed no signs of tumor recurrence.</p>

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The Clear Cell Odontogenic Carcinoma: Case Report of a Rare Jaw Malignancy

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月11日

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  • Vasco Starke,
  • Markus Merkl,
  • Lukas Grössing,
  • Mauro Pau,
  • Wolfgang Zemann

摘要

Clear cell odontogenic carcinoma is a very rare malignant tumor of the jaw. Diagnosis and treatment may be challenging as the tumor grows locally aggressive and infiltrative with possible metastatic spread, while the clinical presentation varies, and the definitive diagnosis can only be confirmed by immunohistopathology. The case of a 25-year-old male patient with clear cell odontogenic carcinoma of the mandible is presented. Therapeutic treatment included primary surgical resection with bilateral removal of cervical lymph nodes followed by a two-stage reconstruction approach. Continuous follow-up over 7.5 years showed no signs of tumor recurrence.