Objectives <p>To evaluate the accuracy of static and dynamic computer-assisted implant surgery during dental implant placement.</p> Material and Methods <p>A literature search was performed for articles evaluating the accuracy of implant placement using static and dynamic computer-assisted implant surgery in four electronic databases. Accuracy of implant placement was evaluated based on the platform, angular and apex deviations as the outcome measures. The Cochrane Risk of Bias tool (RoB 2) was used to evaluate the risk of bias (ROB) in the included articles. The fixed effect model was used for statistical analyses of the pooled data from the included studies. The overall quality of evidence was assessed using the GRADEpro GDT software.</p> Results <p>Three RCTs were selected based on the inclusion and exclusion criteria. The overall ROB was low in one study, and some concerns in two studies. The pooled data from the included trials have shown that the platform (MD, 0.12; CI, −0.04 to 0.27, <i>P</i> = 0.15, I² = 0%) and angular deviation (MD, 0.03; CI, −0.50 to 0.56, <i>P</i> = 0.92, I² = 0%) are higher in the dynamic computer-assisted implant surgical (D-CAIS) technique. The apex deviation is higher in the static computer-assisted implant surgical (S-CAIS) technique (MD, −0.05; CI, −0.23 to 0.13, <i>P</i> = 0.61, I² = 10%) with no statistically significant difference. The overall quality of evidence for all the outcomes assessed is “moderate.”</p> Conclusion <p>The platform and angular deviations are higher in the D-CAIS, and the apex deviation is higher in the S-CAIS with no statistically significant difference. </p> Graphical Abstract <p></p>