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<p>This study investigates the physicochemical properties, fatty acid profile, tocopherol and sterol composition of <i>Marrubium vulgare</i> seed oil (MVSO), with the aim of evaluating its potential for nutritional and industrial applications. The seeds exhibit a high reproductive capacity and yield an oil content of 24.8% through Soxhlet extraction using hexane. GC-MS analysis revealed that MVSO is rich in unsaturated fatty acids, with oleic (44.86%), linoleic (23.74%), and linolenic acids (22.56%) as major constituents. The oil’s favorable omega-6/omega-3 ratio (1.05), high PUFA/SFA ratio (4.56), and low atherogenicity (0.097) and thrombogenicity (0.086) indices support its cardiovascular benefits. Physicochemical analysis demonstrated good oxidative stability, attributed to its high total tocopherol content (1280&#xa0;mg/kg), predominantly γ-tocopherol. MVSO also presented a high iodine value (140.4&#xa0;g I₂/100&#xa0;g), low viscosity (38.7&#xa0;mm²/s), and significant unsaponifiable matter (1.42%), highlighting its suitability for diverse industrial uses. The sterol profile was dominated by β-sitosterol (47.8%) and included high levels of Δ<sup>5</sup>-avenasterol and stigmasterol. Overall, MVSO shows strong promise as a functional oil for use in food, cosmetic, and pharmaceutical formulations.</p>

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Physicochemical Properties and Bioactive Lipid Composition of Marrubium Vulgare Seed Oil

  • 期刊论文

  • 发表日期：

    2025年9月16日

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  • Belsem Jedidi,
  • Hassen Mohamed Sbihi

摘要

This study investigates the physicochemical properties, fatty acid profile, tocopherol and sterol composition of Marrubium vulgare seed oil (MVSO), with the aim of evaluating its potential for nutritional and industrial applications. The seeds exhibit a high reproductive capacity and yield an oil content of 24.8% through Soxhlet extraction using hexane. GC-MS analysis revealed that MVSO is rich in unsaturated fatty acids, with oleic (44.86%), linoleic (23.74%), and linolenic acids (22.56%) as major constituents. The oil’s favorable omega-6/omega-3 ratio (1.05), high PUFA/SFA ratio (4.56), and low atherogenicity (0.097) and thrombogenicity (0.086) indices support its cardiovascular benefits. Physicochemical analysis demonstrated good oxidative stability, attributed to its high total tocopherol content (1280 mg/kg), predominantly γ-tocopherol. MVSO also presented a high iodine value (140.4 g I₂/100 g), low viscosity (38.7 mm²/s), and significant unsaponifiable matter (1.42%), highlighting its suitability for diverse industrial uses. The sterol profile was dominated by β-sitosterol (47.8%) and included high levels of Δ5-avenasterol and stigmasterol. Overall, MVSO shows strong promise as a functional oil for use in food, cosmetic, and pharmaceutical formulations.