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Purpose of Review <p>With emerging data offering evidence to support the omission of sentinel lymph node biopsy (SLNB) in select patients, adoption of these data into practice presents challenges in counseling at the individual patient level and in iterating the workflows within the complex healthcare ecosystem. The purpose of this review is to summarize the recent evidence on omission of SLNB and discuss implications for changing practice.</p> Recent Findings <p>Data from recent trials support a diminishing role of surgical axillary staging, particularly in older women with low-grade, hormone receptor (HR)-positive, HER2-negative, T1-T2 tumors, with equivalent oncologic outcomes and improved quality of life.</p> Summary <p>In selected patient populations who will be receiving multimodality treatment of their breast cancer, omission of SLNB can be offered when appropriate.</p>

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Omitting Sentinel Node Biopsy: Choosing Wisely, Sound, Insema and Beyond

  • 期刊论文

  • 发表日期：

    2026年4月14日

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  • Kimberly M. Brown,
  • Roshni Rao

摘要

Purpose of Review

With emerging data offering evidence to support the omission of sentinel lymph node biopsy (SLNB) in select patients, adoption of these data into practice presents challenges in counseling at the individual patient level and in iterating the workflows within the complex healthcare ecosystem. The purpose of this review is to summarize the recent evidence on omission of SLNB and discuss implications for changing practice.

Recent Findings

Data from recent trials support a diminishing role of surgical axillary staging, particularly in older women with low-grade, hormone receptor (HR)-positive, HER2-negative, T1-T2 tumors, with equivalent oncologic outcomes and improved quality of life.

Summary

In selected patient populations who will be receiving multimodality treatment of their breast cancer, omission of SLNB can be offered when appropriate.