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Purpose of review <p>This systematic review evaluated opioid consumption and associated outcomes among breast cancer patients in the United States (US) who underwent curative surgery.</p> Recent findings <p>A total of 11 studies involving 97,093 patients met inclusion criteria. Postoperative opioid use was common, with considerable variation in prescribing practices. Several interventions, including liposomal bupivacaine, opioid-free anesthesia, and prepectoral reconstruction, were associated with reduced opioid use, improved pain control, shorter hospital stays, and fewer opioid-related adverse events such as nausea and vomiting.</p> Summary <p>Although postoperative opioid use is common among patients undergoing breast cancer surgery, implementation of alternative pain management strategies and opioid-minimizing protocols can potentially reduce opioid consumption and opioid-related adverse events while improving patient outcomes.</p>

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Postoperative Opioid Use and Associated Outcomes after Breast Cancer Surgery in the United States: A Systematic Review

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年1月9日

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  • Prajakta Masurkar,
  • Prachi Prajapati,
  • Joanne Canedo,
  • Sanika Rege,
  • Swarnali Goswami

摘要

Purpose of review

This systematic review evaluated opioid consumption and associated outcomes among breast cancer patients in the United States (US) who underwent curative surgery.

Recent findings

A total of 11 studies involving 97,093 patients met inclusion criteria. Postoperative opioid use was common, with considerable variation in prescribing practices. Several interventions, including liposomal bupivacaine, opioid-free anesthesia, and prepectoral reconstruction, were associated with reduced opioid use, improved pain control, shorter hospital stays, and fewer opioid-related adverse events such as nausea and vomiting.

Summary

Although postoperative opioid use is common among patients undergoing breast cancer surgery, implementation of alternative pain management strategies and opioid-minimizing protocols can potentially reduce opioid consumption and opioid-related adverse events while improving patient outcomes.