<p>The Shack-Hartmann sensor is widely used in research studies to investigate the effects of refractive errors on vision and to develop new treatments for vision disorders. By using this sensor, researchers can gain insight into the wavefront aberrations caused by Presbyopia. In this study, using advanced simulation methods and wavefront aberration analysis, we demonstrate the significant impact of higher-order aberrations on visual quality in individuals with presbyopia. By examining the wavefront maps, focal spot diagrams, Zernike coefficients, and modulation transfer function (MTF) diagrams, we gained valuable insights into the optical behavior of the eye in individuals with presbyopia and refractive errors. Our findings highlight the importance of considering pupil size and refractive errors in the development of effective treatments for presbyopia.</p>