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<p>We propose two approaches to a model deduction for Buruli ulcer spread in a tissue, prove global existence of solutions to the obtained macroscopic cross-diffusion PDE-ODE systems, and perform numerical simulations to illustrate the behavior of solutions under various scenarios and compare the outcome of the two approaches.</p>

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Mathematical modeling of Buruli ulcer spread

  • 期刊论文

  • 发表日期：

    2026年5月29日

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  • Shimi Chettiparambil Mohanan,
  • Christina Surulescu,
  • Neslihan Nesliye Pelen

摘要

We propose two approaches to a model deduction for Buruli ulcer spread in a tissue, prove global existence of solutions to the obtained macroscopic cross-diffusion PDE-ODE systems, and perform numerical simulations to illustrate the behavior of solutions under various scenarios and compare the outcome of the two approaches.