<p>Guaranteeing global food security is one of the greatest challenges of the 21^st century, mostly due to defense measures such as border restrictions resulting from the COVID-19 pandemic, the ongoing conflicts in Russia-Ukraine and Israel-Gaza, and climate change. For this reason, this study empirically explores the simultaneous dynamic effects of agricultural trade liberalization, climate variability and change, and governance quality on food security in the ASEAN member states from 2003 to 2022. Deploying advanced techniques to tackle cross-sectional dependence, serial autocorrelation, and heteroskedasticity while offering robust standard errors in panel data through panel corrected standard errors (PCSE) and feasible generalized least squares (FGLS), as well as the Driscoll-Kraay standard error and one-step system generalized method of moments (GMM) approaches for robustness, the empirical findings prove that agricultural trade openness significantly improves all pillars of food security. Additionally, being open to agricultural exports and imports greatly helps improve nearly all aspects of food security in the ASEAN region, except for food stability, where more agricultural imports actually lead to greater fluctuations in the amount of food available per person. As expected, climate change negatively impacts food security, although strengthened governance quality promotes the improvement of food availability and utilization in ASEAN. Besides, GDP per capita seems to enhance food security, but GDP growth tends to elevate the prevalence of undernourishment and diminish food stability in the region. This study unveils key policy implications for attaining food security in the ASEAN region through fostering collaboration within ASEAN and with its trading partners, as well as advocating for sustainable agricultural practices and climate adaptation.</p>