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<p>Hepatic sarcomatoid carcinoma (HSC) is a rare and highly aggressive subtype of primary liver cancer with no established treatment for unresectable cases. We report the case of a 71-year-old woman with unresectable HSC who achieved complete remission following carbon-ion radiotherapy. The patient exhibited a favorable response to primary tumor and lymph node metastases, with no recurrence observed after 17&#xa0;months. This case highlights the potential efficacy of heavy-ion therapy as a promising alternative for managing HSC.</p>

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First report of metabolic complete response in hepatic sarcomatoid carcinoma achieved with carbon-ion radiotherapy

  • 期刊论文

  • 发表日期：

    2025年7月4日

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  • Ryu Takakura,
  • Yoshiyuki Ota,
  • Yuki Yamazaki,
  • Satoru Iwamoto,
  • Koki Kurouchi,
  • Koki Moriyoshi,
  • Shin’ichi Miyamoto

摘要

Hepatic sarcomatoid carcinoma (HSC) is a rare and highly aggressive subtype of primary liver cancer with no established treatment for unresectable cases. We report the case of a 71-year-old woman with unresectable HSC who achieved complete remission following carbon-ion radiotherapy. The patient exhibited a favorable response to primary tumor and lymph node metastases, with no recurrence observed after 17 months. This case highlights the potential efficacy of heavy-ion therapy as a promising alternative for managing HSC.