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<p>We describe three cases in which plasmapheresis was effective for persistent obstructive jaundice, even after biliary drainage. All three cases involved resectable or borderline resectable malignant tumors that caused obstructive jaundice. Jaundice is refractory to biliary drainage and medication and results in prolonged hyperbilirubinemia. Plasmapheresis led to improvements in all cases. Plasmapheresis may be a treatment option for persistent obstructive jaundice resistant to standard therapies.</p>

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Three cases in which plasmapheresis was effective for persistent obstructive jaundice due to malignant biliary obstruction after biliary drainage

  • 期刊论文

  • 发表日期：

    2025年6月22日

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  • Yuhei Iwasa,
  • Keisuke Iwata,
  • Ryuichi Tezuka,
  • Takuji Iwashita,
  • Shinya Uemura,
  • Shota Iwata,
  • Yosuke Ohashi,
  • Yuki Murayama,
  • Masahito Shimizu

摘要

We describe three cases in which plasmapheresis was effective for persistent obstructive jaundice, even after biliary drainage. All three cases involved resectable or borderline resectable malignant tumors that caused obstructive jaundice. Jaundice is refractory to biliary drainage and medication and results in prolonged hyperbilirubinemia. Plasmapheresis led to improvements in all cases. Plasmapheresis may be a treatment option for persistent obstructive jaundice resistant to standard therapies.