Scholarlink

<p>Anal canal cancer (ACC) is a rare yet noteworthy malignancy that is strongly associated with high-risk human papillomaviruses (HPVs). This case report highlights the diagnostic utility of endocytoscopy (EC) in distinguishing high-grade squamous intraepithelial lesions (HSILs) from low-grade lesions (LSILs) in a 57-year-old male presenting with hematochezia. Traditional magnifying endoscopy was inconclusive; however, EC provided detailed visualization of cellular and vascular changes, facilitating a diagnosis of HPV-associated HSIL or carcinoma in situ. Subsequent en bloc resection by endoscopic submucosal dissection was performed successfully, with no recurrence at the 6-month follow-up. This case underscores the value of EC in enhancing diagnostic accuracy for anal lesions, suggesting potential benefits for broader diagnostic applications.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Real-time diagnosis of a lesion of the anal canal observed by endocytoscopy

  • 期刊论文

  • 发表日期：

    2025年1月6日

查看全文
  • Taishi Okumura,
  • Kinichi Hotta,
  • Daisuke Aizawa,
  • Kenichiro Imai,
  • Sayo Ito,
  • Kazunori Takada,
  • Tadakazu Shimoda,
  • Hiroyuki Ono

摘要

Anal canal cancer (ACC) is a rare yet noteworthy malignancy that is strongly associated with high-risk human papillomaviruses (HPVs). This case report highlights the diagnostic utility of endocytoscopy (EC) in distinguishing high-grade squamous intraepithelial lesions (HSILs) from low-grade lesions (LSILs) in a 57-year-old male presenting with hematochezia. Traditional magnifying endoscopy was inconclusive; however, EC provided detailed visualization of cellular and vascular changes, facilitating a diagnosis of HPV-associated HSIL or carcinoma in situ. Subsequent en bloc resection by endoscopic submucosal dissection was performed successfully, with no recurrence at the 6-month follow-up. This case underscores the value of EC in enhancing diagnostic accuracy for anal lesions, suggesting potential benefits for broader diagnostic applications.