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<p>The dengue virus is an RNA virus endemic to the tropics and subtropics and transmitted to humans through the bite of infected mosquitoes. While many primary dengue virus infections are asymptomatic or only mildly symptomatic, the risk of a severe course in the context of second infections is increased by a&#xa0;factor of 2–3. Treatment is purely symptomatic and the administration of nonsteroidal anti-inflammatory drugs (NSAID) should be avoided due to the increased risk of bleeding. Serological tests and the reverse transcription polymerase chain reaction (RT-PCR) are the main diagnostic tools. Repellents with a&#xa0;high diethyltoluamide (DEET) content, mosquito nets and suitable clothing are used for prevention. In the European union two live vaccines against the dengue virus have been approved. Currently there is no general recommendation for vaccination against dengue fever as severe cases have been observed after vaccination and first infection. Vaccination can be carried out after a&#xa0;risk-benefit assessment. Vector control is the most important factor in the prevention and control of dengue virus infections.</p>

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Ein Souvenir aus Indonesien

  • 期刊论文

  • 发表日期：

    2025年1月27日

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  • Constanze Offner,
  • Susanne Seitz,
  • Richard Stockinger,
  • Susanna Neumayer,
  • Isabella Obwegeser,
  • Robert Strohal,
  • Nina Häring

摘要

The dengue virus is an RNA virus endemic to the tropics and subtropics and transmitted to humans through the bite of infected mosquitoes. While many primary dengue virus infections are asymptomatic or only mildly symptomatic, the risk of a severe course in the context of second infections is increased by a factor of 2–3. Treatment is purely symptomatic and the administration of nonsteroidal anti-inflammatory drugs (NSAID) should be avoided due to the increased risk of bleeding. Serological tests and the reverse transcription polymerase chain reaction (RT-PCR) are the main diagnostic tools. Repellents with a high diethyltoluamide (DEET) content, mosquito nets and suitable clothing are used for prevention. In the European union two live vaccines against the dengue virus have been approved. Currently there is no general recommendation for vaccination against dengue fever as severe cases have been observed after vaccination and first infection. Vaccination can be carried out after a risk-benefit assessment. Vector control is the most important factor in the prevention and control of dengue virus infections.