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Introduction <p>Intercostal neuralgia is a neuropathic pain arising from the intercostal nerves and commonly presents as sharp and burning pain along the chest wall following surgical interventions, neuroma formation, or post-herpetic neuralgia. Conservative treatments include medical management with anti-inflammatory drugs, neuropathic medications, opioids, and intercostal nerve blocks. Radiofrequency ablation (RFA) is a minimally invasive procedure that has been shown to offer pain relief for patients with intercostal neuralgia refractory to conservative measures. This article discusses anatomical considerations and interventional approaches for RFA of the intercostal nerves. These approaches consider anatomical differences, such as the Kuntz nerve and uncommon nerve branches, to enhance accuracy, clinical efficacy, and safety.</p> Results <p>Preliminary clinical experience and anatomical analysis suggest this image-guided RFA technique improves procedural safety and targeting accuracy. Early outcomes indicate improved pain control in patients with chronic intercostal neuralgia, with reduced risk of complications and better preservation of motor and sympathetic function.</p> Conclusion <p>RFA effectively treats intercostal neuralgia refractory to conservative measures. Successful treatment of intercostal neuralgia with RFA relies on a strong anatomical understanding and proper technical approaches outlined in this study.</p>

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Intercostal Nerve Radiofrequency Ablation: A Comprehensive Review of Evolving Techniques and Clinical Applications

  • 期刊论文

  • 发表日期：

    2026年3月24日

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  • Alaa Abd-Elsayed,
  • Shahnaz Fooladi,
  • Barnabas T. Shiferaw

摘要

Introduction

Intercostal neuralgia is a neuropathic pain arising from the intercostal nerves and commonly presents as sharp and burning pain along the chest wall following surgical interventions, neuroma formation, or post-herpetic neuralgia. Conservative treatments include medical management with anti-inflammatory drugs, neuropathic medications, opioids, and intercostal nerve blocks. Radiofrequency ablation (RFA) is a minimally invasive procedure that has been shown to offer pain relief for patients with intercostal neuralgia refractory to conservative measures. This article discusses anatomical considerations and interventional approaches for RFA of the intercostal nerves. These approaches consider anatomical differences, such as the Kuntz nerve and uncommon nerve branches, to enhance accuracy, clinical efficacy, and safety.

Results

Preliminary clinical experience and anatomical analysis suggest this image-guided RFA technique improves procedural safety and targeting accuracy. Early outcomes indicate improved pain control in patients with chronic intercostal neuralgia, with reduced risk of complications and better preservation of motor and sympathetic function.

Conclusion

RFA effectively treats intercostal neuralgia refractory to conservative measures. Successful treatment of intercostal neuralgia with RFA relies on a strong anatomical understanding and proper technical approaches outlined in this study.