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Introduction <p>To estimate the recording rates and impact of overweight/obesity across selected countries in Europe and Asia–Pacific.</p> Methods <p>IMPACT-O was a retrospective cohort study of electronic medical records and claims databases from France, Germany, Italy, Spain, the UK, Australia, and Japan. Recording levels and the number of adults with overweight/obesity [based on diagnostic codes and/or body mass index (BMI)] during 2018–2022 were estimated. BMI thresholds/categories and obesity-related complications (ORCs) were described for adults with&#xa0;≥&#xa0;1 BMI record of&#xa0;≥&#xa0;25.0 kg/m<sup>2</sup> and&#xa0;≥&#xa0;12 months observation before the index date.</p> Results <p>The number of active subjects across databases ranged from 1,203,674 to 22,413,902. BMI was recorded for 4.8–38.9% of active patients. The number of adults with overweight/obesity ranged from 3.5% in Australia to 24.9% in the UK. The percentage of individuals with BMI&#xa0;&gt;&#xa0;25 to&#xa0;&lt;&#xa0;30 kg/m<sup>2</sup> ranged from 43.6% in Spain to 77.9% in Japan; the percentage with BMI&#xa0;≥&#xa0;30.0 kg/m<sup>2</sup> ranged from 22.1% in Japan to 54.8% in Spain. Among those with overweight/obesity, the percentage with diagnosis codes in their records ranged from 2.9% in France to 50.1% in Germany. Most (59.6–85.0%) individuals had&#xa0;≥&#xa0;1 ORC; 35.9–65.8% had multimorbidity. The most frequently recorded ORCs were hypertension, dyslipidemia, depression, and type 2 diabetes.</p> Conclusion <p>Only a small proportion of people with overweight/obesity are formally diagnosed in healthcare databases. Most present with&#xa0;≥&#xa0;1 ORC, commonly hypertension, dyslipidemia, depression, and type 2 diabetes.</p>

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Epidemiology Landscape and Impact of Overweight and Obesity in Adults: Multi-country Results from the IMPACT-O Study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年8月19日

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  • Esther Artime,
  • Erik Spaepen,
  • Sarah Zimner-Rapuch,
  • Anastasia Lampropoulou,
  • Atif Adam,
  • Xiaoyu Lin,
  • Mengyuan Shang,
  • Sarah Seager,
  • Carel W. Le Roux,
  • Dror Dicker

摘要

Introduction

To estimate the recording rates and impact of overweight/obesity across selected countries in Europe and Asia–Pacific.

Methods

IMPACT-O was a retrospective cohort study of electronic medical records and claims databases from France, Germany, Italy, Spain, the UK, Australia, and Japan. Recording levels and the number of adults with overweight/obesity [based on diagnostic codes and/or body mass index (BMI)] during 2018–2022 were estimated. BMI thresholds/categories and obesity-related complications (ORCs) were described for adults with ≥ 1 BMI record of ≥ 25.0 kg/m2 and ≥ 12 months observation before the index date.

Results

The number of active subjects across databases ranged from 1,203,674 to 22,413,902. BMI was recorded for 4.8–38.9% of active patients. The number of adults with overweight/obesity ranged from 3.5% in Australia to 24.9% in the UK. The percentage of individuals with BMI > 25 to < 30 kg/m2 ranged from 43.6% in Spain to 77.9% in Japan; the percentage with BMI ≥ 30.0 kg/m2 ranged from 22.1% in Japan to 54.8% in Spain. Among those with overweight/obesity, the percentage with diagnosis codes in their records ranged from 2.9% in France to 50.1% in Germany. Most (59.6–85.0%) individuals had ≥ 1 ORC; 35.9–65.8% had multimorbidity. The most frequently recorded ORCs were hypertension, dyslipidemia, depression, and type 2 diabetes.

Conclusion

Only a small proportion of people with overweight/obesity are formally diagnosed in healthcare databases. Most present with ≥ 1 ORC, commonly hypertension, dyslipidemia, depression, and type 2 diabetes.