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<p>DVT and/or PE collectively constitute what is known as venous thromboembolism (VTE).Data on the clinical presentation, risk factors, and short-term outcomes of VTE in the Indian emergency care setting are limited.This observational prospective study recruited patients &gt; 18 years with diagnosis of deep vein thrombosis and cerebral venous thrombosis confirmed on duplex ultrasonography and MRI/MR venography respectively over period of 15 months. Among 96 patients with radiologically proven acute DVT or CVT; 81.2% had DVT and 18.8% CVT with mean age of 43.3 ± 11.2 years. DVT was more prevalent in cases aged &gt; 40 years (47 cases (60.2%) vs. 31 cases (39.8%), while CVT was found to be more common in subjects with age &lt; 40 years (16(88.9%) vs. 2(11.1%). In 78 cases with DVT 67.9% (<i>n</i> = 53) were males and 32.1% (<i>n</i> = 25) were females with a similar trend seen in 18 cases of CVT (72.2% vs. 27.8%)0.63.5% did not have risk factors; among DVT 37.2% and among CVT 11.1% had identifiable risk factors like malignancy, immobilization, OCP use and Factor V Leiden mutation etc. Popliteal vein involvement was most common (90.9%). Superior sagittal sinus was the most frequently involved sinus (83%).D-Dimer was elevated in 90% of cases. 19.2% had a modified Wells score &gt; 4, correlating significantly with DVT occurrence. At the 3-month follow-up, (91%) of DVT and 94.4% of CVT cases achieved therapeutic anticoagulation. <b>Conclusion</b>: DVT was common in men &gt; 40 yrs, CVT in &lt; 40 yrs, with malignancy and Factor V Leiden as key risk factors with Wells Score effectively predicted PE.</p>

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Acute Venous Thrombosis in the Emergency Department: Clinical Profile and Outcomes from a Tertiary Care Centre in North India

  • 期刊论文

  • 发表日期：

    2026年1月12日

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  • Prashant Gupta,
  • Vikas Suri,
  • Savita Kumari,
  • Harpreet Singh,
  • Deba Prasad Dhibar,
  • Arihant Jain,
  • Pankaj Malhotra,
  • Ashish Bhalla,
  • Jasmina Ahluwalia,
  • Ujjwal Gorsi,
  • Chirag Kamal Ahuja,
  • Aastha Takkar

摘要

DVT and/or PE collectively constitute what is known as venous thromboembolism (VTE).Data on the clinical presentation, risk factors, and short-term outcomes of VTE in the Indian emergency care setting are limited.This observational prospective study recruited patients > 18 years with diagnosis of deep vein thrombosis and cerebral venous thrombosis confirmed on duplex ultrasonography and MRI/MR venography respectively over period of 15 months. Among 96 patients with radiologically proven acute DVT or CVT; 81.2% had DVT and 18.8% CVT with mean age of 43.3 ± 11.2 years. DVT was more prevalent in cases aged > 40 years (47 cases (60.2%) vs. 31 cases (39.8%), while CVT was found to be more common in subjects with age < 40 years (16(88.9%) vs. 2(11.1%). In 78 cases with DVT 67.9% (n = 53) were males and 32.1% (n = 25) were females with a similar trend seen in 18 cases of CVT (72.2% vs. 27.8%)0.63.5% did not have risk factors; among DVT 37.2% and among CVT 11.1% had identifiable risk factors like malignancy, immobilization, OCP use and Factor V Leiden mutation etc. Popliteal vein involvement was most common (90.9%). Superior sagittal sinus was the most frequently involved sinus (83%).D-Dimer was elevated in 90% of cases. 19.2% had a modified Wells score > 4, correlating significantly with DVT occurrence. At the 3-month follow-up, (91%) of DVT and 94.4% of CVT cases achieved therapeutic anticoagulation. Conclusion: DVT was common in men > 40 yrs, CVT in < 40 yrs, with malignancy and Factor V Leiden as key risk factors with Wells Score effectively predicted PE.