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<p>This first report described a 65-year-old female with AML with MECOM rearrangement, presenting with prominent hemophagocytosis. The case met WHO-HAEM5 diagnostic criteria despite &lt; 20% blasts, highlighting both a novel clinical feature and the diagnostic challenge posed by differing classification systems.</p>

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Acute Myeloid Leukemia with MECOM Rearrangement Presenting with Striking Hemophagocytosis

  • 期刊论文

  • 发表日期：

    2025年11月13日

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  • Hongwei Chen,
  • Meixuan Chen

摘要

This first report described a 65-year-old female with AML with MECOM rearrangement, presenting with prominent hemophagocytosis. The case met WHO-HAEM5 diagnostic criteria despite < 20% blasts, highlighting both a novel clinical feature and the diagnostic challenge posed by differing classification systems.