<p>Procedures in the oral and maxillofacial region are increasingly performed in patients receiving oral anticoagulation or antiplatelet therapy. This requires clinicians to carefully balance the risk of peri- and postoperative bleeding against the potentially serious risk of thromboembolic events associated with modification of antithrombotic medication. This article presents a&#xa0;structured, practice-oriented approach to perioperative management of oral anticoagulation. The focus is placed on preoperative assessment of medical history, evaluation of the procedure-related bleeding risk, and individualized estimation of the thromboembolic risk based on the underlying indication for antithrombotic therapy. The relevant pharmacological agents are discussed with regard to their implications for surgical planning. Particular emphasis is placed on local haemostatic measures and on identifying clinical situations in which interdisciplinary consultation or inpatient management may be required.</p>

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Perioperativer Umgang mit oraler Gerinnungshemmung bei Eingriffen im Mund- und Kieferbereich

  • P. W. Kämmerer

摘要

Procedures in the oral and maxillofacial region are increasingly performed in patients receiving oral anticoagulation or antiplatelet therapy. This requires clinicians to carefully balance the risk of peri- and postoperative bleeding against the potentially serious risk of thromboembolic events associated with modification of antithrombotic medication. This article presents a structured, practice-oriented approach to perioperative management of oral anticoagulation. The focus is placed on preoperative assessment of medical history, evaluation of the procedure-related bleeding risk, and individualized estimation of the thromboembolic risk based on the underlying indication for antithrombotic therapy. The relevant pharmacological agents are discussed with regard to their implications for surgical planning. Particular emphasis is placed on local haemostatic measures and on identifying clinical situations in which interdisciplinary consultation or inpatient management may be required.