Scholarlink

Background <p>Presenteeism among working-age breast cancer survivors drives job loss and economic burden, but the extent to which it is attributable to treatment-related symptoms remains unclear. We examined determinants of presenteeism severity 1–5&#xa0;years after surgery and preferences for support.</p> Methods <p>In this cross-sectional study, presenteeism was assessed with the Work Productivity and Activity Impairment questionnaire in 203 employed survivors (&lt; 65&#xa0;years) 1–5&#xa0;years post-surgery. Presenteeism was modeled using hierarchical multiple linear regression with four blocks: (1) patient characteristics/treatment exposures; (2) work-related factors; (3) psychological symptoms and health literacy; and (4) physical function and cancer treatment-related symptoms. A modifiable-only sensitivity model with prespecified clinical cutoffs was also estimated.</p> Results <p>Presenteeism was present in 55.7% and severe in 27.1%. Model fit improved stepwise, with the largest incremental variance at Step 4. In the final model, higher presenteeism was independently associated with aromatase inhibitor–induced musculoskeletal symptoms, postmastectomy pain syndrome, greater cancer-related fatigue, reduced shoulder range of motion, and non–desk-based work (all <i>p</i> &lt; 0.05). Over 70% preferred physiotherapy or pharmacotherapy.</p> Conclusion <p>Presenteeism in working-age survivors of breast cancer was strongly associated with modifiable treatment-related symptoms. Based on our findings, multidisciplinary, patient-centered interventions are recommended to support job retention and reintegration.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Presenteeism in working-age breast cancer survivors 1–5 years after surgery: relative contributions of treatment-related symptoms and modifiable factors

  • 期刊论文

  • 发表日期：

    2026年2月9日

查看全文
  • Masahiro Manfuku,
  • Ryota Imai,
  • Satoko Yono,
  • Hiroe Kanamori,
  • Kazuhiro Sumiyoshi

摘要

Background

Presenteeism among working-age breast cancer survivors drives job loss and economic burden, but the extent to which it is attributable to treatment-related symptoms remains unclear. We examined determinants of presenteeism severity 1–5 years after surgery and preferences for support.

Methods

In this cross-sectional study, presenteeism was assessed with the Work Productivity and Activity Impairment questionnaire in 203 employed survivors (< 65 years) 1–5 years post-surgery. Presenteeism was modeled using hierarchical multiple linear regression with four blocks: (1) patient characteristics/treatment exposures; (2) work-related factors; (3) psychological symptoms and health literacy; and (4) physical function and cancer treatment-related symptoms. A modifiable-only sensitivity model with prespecified clinical cutoffs was also estimated.

Results

Presenteeism was present in 55.7% and severe in 27.1%. Model fit improved stepwise, with the largest incremental variance at Step 4. In the final model, higher presenteeism was independently associated with aromatase inhibitor–induced musculoskeletal symptoms, postmastectomy pain syndrome, greater cancer-related fatigue, reduced shoulder range of motion, and non–desk-based work (all p < 0.05). Over 70% preferred physiotherapy or pharmacotherapy.

Conclusion

Presenteeism in working-age survivors of breast cancer was strongly associated with modifiable treatment-related symptoms. Based on our findings, multidisciplinary, patient-centered interventions are recommended to support job retention and reintegration.