Purpose of Review <p>The zoonotic nature of various dermatophytes poses a threat to both animals and humans. Increasing antibiotic resistance among several dermatophytes has raised the risk of treatment failure. The current review summarises the efficacy of biosurfactants as a green alternative to treat dermatophytosis.</p> Recent Findings <p>Although there are various reports about the antimicrobial activity of different biosurfactants, limited studies and reviews have been conducted on the usefulness of biosurfactants to treat dermatophytosis. Latest reports have unequivocally proved the antifungal efficacy of various biosurfactants against common dermatophytes. The current review discusses the findings of research works carried out globally in this aspect and highlights the market potential of biosurfactants as antidermatophytic agents.</p> Summary <p>The present review focuses on the importance of biosurfactants as potential antifungal agents against dermatophytosis in humans and animals. It also emphasizes use of biosurfactants as a replacement to chemically synthesised antifungals for the treatment of dermatophytosis.</p>