Scholarlink

Purpose of Review <p>This review aims to summarize current knowledge on the transmission, diagnostics, treatment, and control of sporotrichosis, a global mycosis affecting humans and cats, with a focus on recent taxonomic developments and the rise of cat-transmitted cases.</p> Recent Findings <p><i>Sporothrix&#xa0;</i>has undergone considerable taxonomic shifts, with 70 species recognized, each exhibiting diverse biological characteristics and ecological niches, which include pathogens affecting mammals, plants, and insects, as well as fungicolous species. Sporotrichosis is transmitted primarily through the traumatic inoculation of contaminated plant material, but animal-mediated transmission, chiefly via cats infected with highly virulent <i>S. brasiliensis</i>, has increased dramatically. This shift in transmission patterns has led to significant outbreaks, especially in South America, raising concerns about the potential for global dissemination. Advances in PCR-based diagnostics have revolutionized species identification and epidemiological tracking, enabling a deeper understanding of disease transmission dynamics and the genetic diversity of <i>Sporothrix</i>. Genotyping studies have provided insights into the population structure, evolutionary relationships, and potential adaptations of <i>Sporothrix</i>, revealing the complex interplay between human activities, animal interactions, and environmental changes in shaping the distribution of <i>Sporothrix</i> species.</p> Summary <p>The increasing global incidence of sporotrichosis underscores the need for improved surveillance, better diagnostic accessibility, and more affordable molecular tests. Effective control strategies, including public awareness and responsible animal management, are essential to address the growing global threat of sporotrichosis.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Insights from Cutting-edge Diagnostics and Epidemiology of Sporotrichosis and Taxonomic Shifts in Sporothrix

  • 期刊论文

  • 发表日期：

    2025年2月18日

查看全文
  • Thiago Costa Machado,
  • Sarah Santos Gonçalves,
  • Jamile Ambrósio de Carvalho,
  • Alexandro Bonifaz,
  • Raimunda Sâmia Nogueira Brilhante,
  • Zoilo Pires de Camargo,
  • Anderson Messias Rodrigues

摘要

Purpose of Review

This review aims to summarize current knowledge on the transmission, diagnostics, treatment, and control of sporotrichosis, a global mycosis affecting humans and cats, with a focus on recent taxonomic developments and the rise of cat-transmitted cases.

Recent Findings

Sporothrix has undergone considerable taxonomic shifts, with 70 species recognized, each exhibiting diverse biological characteristics and ecological niches, which include pathogens affecting mammals, plants, and insects, as well as fungicolous species. Sporotrichosis is transmitted primarily through the traumatic inoculation of contaminated plant material, but animal-mediated transmission, chiefly via cats infected with highly virulent S. brasiliensis, has increased dramatically. This shift in transmission patterns has led to significant outbreaks, especially in South America, raising concerns about the potential for global dissemination. Advances in PCR-based diagnostics have revolutionized species identification and epidemiological tracking, enabling a deeper understanding of disease transmission dynamics and the genetic diversity of Sporothrix. Genotyping studies have provided insights into the population structure, evolutionary relationships, and potential adaptations of Sporothrix, revealing the complex interplay between human activities, animal interactions, and environmental changes in shaping the distribution of Sporothrix species.

Summary

The increasing global incidence of sporotrichosis underscores the need for improved surveillance, better diagnostic accessibility, and more affordable molecular tests. Effective control strategies, including public awareness and responsible animal management, are essential to address the growing global threat of sporotrichosis.