<p>Bacterial populations often appear homogeneous, yet individual cells can differ greatly in their gene activity. New single-cell transcriptomics methods now make it possible to reveal this functional diversity. Highly sensitive approaches such as MATQ-seq enable the detection of hundreds of genes per bacterium and open new possibilities for studying rare cell states and microbial dynamics.</p>

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Gleich und doch verschieden: bakterieller Genexpression auf der Spur

  • Fabian Imdahl,
  • Christina Homberger,
  • Jörg Vogel

摘要

Bacterial populations often appear homogeneous, yet individual cells can differ greatly in their gene activity. New single-cell transcriptomics methods now make it possible to reveal this functional diversity. Highly sensitive approaches such as MATQ-seq enable the detection of hundreds of genes per bacterium and open new possibilities for studying rare cell states and microbial dynamics.