Scholarlink

<p>Cell surface receptors play an intricate role in signaling networks, sensing extracellular stimuli to be translated in intracellularly. Canonical pathways are well-described, yet layers of complexity are added by the multifunctionality introduced through receptor crosstalk. In order to understand mutual influence, chemical biology probes are described for self-labelling enzymes, to visualize and quantify clinically relevant, (co-)internalized receptor pools by high throughput imaging.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Chemisch spaltbare Sonden zur Visualisierung ko-internalisierter Rezeptoren

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年10月8日

查看全文
  • Johannes Broichhagen

摘要

Cell surface receptors play an intricate role in signaling networks, sensing extracellular stimuli to be translated in intracellularly. Canonical pathways are well-described, yet layers of complexity are added by the multifunctionality introduced through receptor crosstalk. In order to understand mutual influence, chemical biology probes are described for self-labelling enzymes, to visualize and quantify clinically relevant, (co-)internalized receptor pools by high throughput imaging.