<p>Embryonic dormancy (diapause) is a reproductive adaptation that allows some mammalian species to halt the otherwise continuous pace of embryonic development. While the dormant embryo remains in a state of suspended animation, molecular analysis at single-cell resolution has revealed extensive signalling, transcriptional and morphogenetic changes, indicating that diapause is not a stasis but a dynamic process.</p>

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Cellular dynamics in the dormant embryo

  • Rui Chen,
  • Ivan Bedzhov

摘要

Embryonic dormancy (diapause) is a reproductive adaptation that allows some mammalian species to halt the otherwise continuous pace of embryonic development. While the dormant embryo remains in a state of suspended animation, molecular analysis at single-cell resolution has revealed extensive signalling, transcriptional and morphogenetic changes, indicating that diapause is not a stasis but a dynamic process.