<p>To investigate the association between cognitive function and postoperative stroke in patients undergoing off-pump coronary artery bypass grafting (CABG). We reviewed patients who underwent cognitive evaluations including Montreal Cognitive Assessment (MoCA), Mini-Mental State Examination (MMSE), Pittsburgh Sleep Quality Index (PSQI), and Activities of Daily Living (ADL) scale before CABG. The association between cognitive function and postoperative stroke was analyzed. A total of 1,932 patients were analyzed. Postoperatively, 34 (1.8%) developed new-onset stroke.Poststroke patients showed lower MMSE (27.0 [23.2–28.0] vs. 28.0 [27.0–29.0], <i>p</i> &lt; 0.001) and MoCA scores (21.0 [18.0–23.8] vs. 24.0 [21.0–27.0], <i>p</i> &lt; 0.001), but similar PSQI and ADL scores compared to those without stroke. After stepwise regression, preoperative stroke (OR = 7.07, <i>p</i> &lt; 0.001) and MoCA scores (OR = 0.90 / point, <i>p</i> = 0.002) were predictors of postoperative stroke. Preoperative cognitive function evaluated by MoCA is associated with postoperative stroke following CABG.</p>

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Association between Cognitive Function and Postoperative Stroke Following Off-Pump Coronary Artery Bypass Grafting

  • Chuanjie Yue,
  • Hao Cui,
  • Jinwei Zhang,
  • Peng Sun,
  • Chenzhen Xu,
  • Tong Tan,
  • Ke Zhang,
  • Song Wang,
  • Zhipeng Wei,
  • Changwei Ren,
  • Yongqiang Lai

摘要

To investigate the association between cognitive function and postoperative stroke in patients undergoing off-pump coronary artery bypass grafting (CABG). We reviewed patients who underwent cognitive evaluations including Montreal Cognitive Assessment (MoCA), Mini-Mental State Examination (MMSE), Pittsburgh Sleep Quality Index (PSQI), and Activities of Daily Living (ADL) scale before CABG. The association between cognitive function and postoperative stroke was analyzed. A total of 1,932 patients were analyzed. Postoperatively, 34 (1.8%) developed new-onset stroke.Poststroke patients showed lower MMSE (27.0 [23.2–28.0] vs. 28.0 [27.0–29.0], p < 0.001) and MoCA scores (21.0 [18.0–23.8] vs. 24.0 [21.0–27.0], p < 0.001), but similar PSQI and ADL scores compared to those without stroke. After stepwise regression, preoperative stroke (OR = 7.07, p < 0.001) and MoCA scores (OR = 0.90 / point, p = 0.002) were predictors of postoperative stroke. Preoperative cognitive function evaluated by MoCA is associated with postoperative stroke following CABG.