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<p>We present a case of an elderly male in his mid-70s who presented to the urology outpatient department with lower urinary tract symptoms (LUTS) and was incidentally detected with a right pelvic mass on evaluation. Contrast-enhanced Computed Tomography (CECT) revealed a solid-cystic right pelvic mass with enhancement. Positron emission tomography (PET) revealed a hypermetabolic soft tissue mass replacing the right seminal vesicle, with no evidence of distant metastasis. Fine-needle aspiration cytology (FNAC) revealed a well differentiated neoplasm. The patient underwent laparoscopic excision of the right pelvic mass and standard pelvic lymph node dissection. Immunohistochemistry confirmed a neuroendocrine neoplasm with positive synaptophysin and chromogranin A staining. On the 6-month follow-up scan, he remained disease-free. This case highlights the challenges faced during the diagnosis and treatment of primary seminal vesicle neuroendocrine tumours.</p>

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Primary Neuroendocrine Tumor of the Seminal Vesicle: A Diagnostic and Therapeutic Challenge

  • 期刊论文

  • 发表日期：

    2026年7月11日

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  • Bhopesh kadian,
  • Saket Singh,
  • Naveen Kumar,
  • Kashif Rizwi,
  • Arvind Kumar

摘要

We present a case of an elderly male in his mid-70s who presented to the urology outpatient department with lower urinary tract symptoms (LUTS) and was incidentally detected with a right pelvic mass on evaluation. Contrast-enhanced Computed Tomography (CECT) revealed a solid-cystic right pelvic mass with enhancement. Positron emission tomography (PET) revealed a hypermetabolic soft tissue mass replacing the right seminal vesicle, with no evidence of distant metastasis. Fine-needle aspiration cytology (FNAC) revealed a well differentiated neoplasm. The patient underwent laparoscopic excision of the right pelvic mass and standard pelvic lymph node dissection. Immunohistochemistry confirmed a neuroendocrine neoplasm with positive synaptophysin and chromogranin A staining. On the 6-month follow-up scan, he remained disease-free. This case highlights the challenges faced during the diagnosis and treatment of primary seminal vesicle neuroendocrine tumours.