Scholarlink

<p>This study evaluated the diagnostic value of the delta neutrophil index and related hematological parameters in distinguishing acute appendicitis between pregnant and non-pregnant women. This retrospective single-center analysis conducted between January and October 2024 included 34 pregnant and 81 non-pregnant patients with histopathologically confirmed appendicitis. Preoperative hematological and biochemical parameters, including white blood cell count, neutrophil and lymphocyte counts, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, delta neutrophil index (DNI), C-reactive protein, alanine aminotransferase, aspartate aminotransferase, and gamma-glutamyl transferase were compared using the Mann–Whitney U test. Median age did not differ between groups (27 [22–30] years vs. 27 [22–30] years; <i>p</i> = 1.000). Pregnant patients had higher neutrophil percentages (81.8 [78.7–86.3] vs. 78.9 [73.3–83.9]; <i>p</i> = 0.020), higher neutrophil-to-lymphocyte ratio (7.68 [5.36–12.65] vs. 5.80 [3.96–7.61]; <i>p</i> = 0.008), and higher delta neutrophil index values (0.06 [0.04–0.10] vs. 0.05 [0.04–0.06]; <i>p</i> = 0.023; DNI%: 0.4 [0.3–0.6] vs. 0.3 [0.3–0.4]; <i>p</i> = 0.003). Lymphocyte counts, lymphocyte percentages, platelet counts, and gamma-glutamyl transferase levels were lower in pregnant patients (all <i>p</i> &lt; 0.05). No significant differences were observed in white blood cell count, neutrophil count, C-reactive protein levels, or appendiceal diameter. Delta neutrophil index, neutrophil-to-lymphocyte ratio, and neutrophil percentage may serve as useful auxiliary indices for the diagnosis of acute appendicitis during pregnancy, particularly in settings where imaging is not readily available.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Diagnostic Significance of Delta Neutrophil Index and Hematology Parameters for Acute Appendicitis in Pregnant Women

  • 期刊论文

  • 发表日期：

    2026年7月20日

查看全文
  • Hakan Hakkoymaz,
  • Murat Tepe,
  • Muhammed Semih Gedik,
  • Ali İhsan Kilci,
  • Erhan Kaya,
  • Mehmet Tatlı,
  • Mürsel Koçer,
  • Muhammed Ali Güler,
  • Seval Akben

摘要

This study evaluated the diagnostic value of the delta neutrophil index and related hematological parameters in distinguishing acute appendicitis between pregnant and non-pregnant women. This retrospective single-center analysis conducted between January and October 2024 included 34 pregnant and 81 non-pregnant patients with histopathologically confirmed appendicitis. Preoperative hematological and biochemical parameters, including white blood cell count, neutrophil and lymphocyte counts, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, delta neutrophil index (DNI), C-reactive protein, alanine aminotransferase, aspartate aminotransferase, and gamma-glutamyl transferase were compared using the Mann–Whitney U test. Median age did not differ between groups (27 [22–30] years vs. 27 [22–30] years; p = 1.000). Pregnant patients had higher neutrophil percentages (81.8 [78.7–86.3] vs. 78.9 [73.3–83.9]; p = 0.020), higher neutrophil-to-lymphocyte ratio (7.68 [5.36–12.65] vs. 5.80 [3.96–7.61]; p = 0.008), and higher delta neutrophil index values (0.06 [0.04–0.10] vs. 0.05 [0.04–0.06]; p = 0.023; DNI%: 0.4 [0.3–0.6] vs. 0.3 [0.3–0.4]; p = 0.003). Lymphocyte counts, lymphocyte percentages, platelet counts, and gamma-glutamyl transferase levels were lower in pregnant patients (all p < 0.05). No significant differences were observed in white blood cell count, neutrophil count, C-reactive protein levels, or appendiceal diameter. Delta neutrophil index, neutrophil-to-lymphocyte ratio, and neutrophil percentage may serve as useful auxiliary indices for the diagnosis of acute appendicitis during pregnancy, particularly in settings where imaging is not readily available.