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<p>Peutz-Jeghers syndrome (PJS) is an inherited condition characterized by hamartomatous polyps in the gastrointestinal tract, typically located in the small bowel and mucocutaneous pigmentation in the perioral and oral mucosa. This is the first report of three simultaneous intussusceptions (i.e. gastroduodenal, jejunojejunal, and ileocolic) in a 21 year old Peut-Jeghers patient. The patient was operated and all three intussusceptions were reduced along with resection of several sizeable polyps. The gastro-duodenal intussusception was reduced manually. The jejunojejunal intussusception was treated with a proximal enterotomy followed by manual reduction. Resection was avoided in the small bowel because of its shorter length due to previous resections. The third intussusception in the ileocolic areas was large and irreducible manually, thus necessitating right hemicolectomy with ileocolic anastomosis, several sizeable polyps were also resected. The patient was discharged on post op day 5 with continuation of oral feed and passage of flatus and feces.</p>

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Successful Management of Simultaneous Gastroduodenal, Jejunojejunal, and Ileocolic Intussusception in a Peutz-Jeghers Patient: A Case-report

  • 期刊论文

  • 发表日期：

    2026年3月14日

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  • Sulaiman Hussain,
  • Bashir Ahmad,
  • Zahoor Ahmad Khan,
  • Zoha Sajid Qureshi

摘要

Peutz-Jeghers syndrome (PJS) is an inherited condition characterized by hamartomatous polyps in the gastrointestinal tract, typically located in the small bowel and mucocutaneous pigmentation in the perioral and oral mucosa. This is the first report of three simultaneous intussusceptions (i.e. gastroduodenal, jejunojejunal, and ileocolic) in a 21 year old Peut-Jeghers patient. The patient was operated and all three intussusceptions were reduced along with resection of several sizeable polyps. The gastro-duodenal intussusception was reduced manually. The jejunojejunal intussusception was treated with a proximal enterotomy followed by manual reduction. Resection was avoided in the small bowel because of its shorter length due to previous resections. The third intussusception in the ileocolic areas was large and irreducible manually, thus necessitating right hemicolectomy with ileocolic anastomosis, several sizeable polyps were also resected. The patient was discharged on post op day 5 with continuation of oral feed and passage of flatus and feces.