Scholarlink

<p>This case report presents a highly unusual occurrence of intrasplenic primaryhepatocellular carcinoma (HCC) arising in ectopic hepatic tissue, with a normal liver. A 41-year-old female underwent laparoscopic splenectomy for a large splenic mass. Histopathological evaluation revealed moderately differentiated hepatocellular carcinoma producing alpha-fetoprotein (AFP) within ectopic hepatic tissue in the spleen. Immunohistochemistry confirmed the diagnosis with positive staining for AFP, Glypican-3, and CK19. The liver biopsy showed normal histology, ruling out synchronous hepatic malignancy. This case highlights the rarity of ectopic hepatic tissue carcinogenesis and emphasizes the need for multidisciplinary management, including advanced imaging, immunohistochemistry, and molecular studies.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

An Extremely Rare Presentation of Intrasplenic Primary Hepatoid Carcinoma in Ectopic Hepatic Tissue with Normal Liver: A Case Report

  • 期刊论文

  • 发表日期：

    2026年2月10日

查看全文
  • Keyur Bhatt

摘要

This case report presents a highly unusual occurrence of intrasplenic primaryhepatocellular carcinoma (HCC) arising in ectopic hepatic tissue, with a normal liver. A 41-year-old female underwent laparoscopic splenectomy for a large splenic mass. Histopathological evaluation revealed moderately differentiated hepatocellular carcinoma producing alpha-fetoprotein (AFP) within ectopic hepatic tissue in the spleen. Immunohistochemistry confirmed the diagnosis with positive staining for AFP, Glypican-3, and CK19. The liver biopsy showed normal histology, ruling out synchronous hepatic malignancy. This case highlights the rarity of ectopic hepatic tissue carcinogenesis and emphasizes the need for multidisciplinary management, including advanced imaging, immunohistochemistry, and molecular studies.