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<p>The purpose of this study was to evaluate how postoperative ileus (POI) in patients was affected by ileostomy closure after preoperative bowel stimulation. A randomized controlled trial (RCT) and non-randomized controlled trial (NRCT) were prospectively collected utilizing the PubMed, Cochrane Library, and MEDLINE databases of published research by comparing the stimulation and non-stimulation of ileostomy prior to closure. The study for this meta-statistical analysis was performed in RevMan 5.4, and the best effect model was chosen based on heterogeneity. A total of 293 patients from six retrospective studies (140 in the intervention group and 153 in the control group) were included, as they met the specified criteria. A statistically significant result was in postoperative ileus (MH =  − 0.16; 95% Cl − 0.24, − 0.08; <i>P</i> = 0.002). Preoperative stimulation was associated with early restoration of bowel function. However, Clavien-Dindo complication III, duration of hospital stays, and first passage of flatus did not prove statistically significant. Preoperative bowel stimulation that restores bowel function following ileostomy has a significant impact on postoperative ileus.</p>

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Preoperative Bowel Stimulation Reduces Postoperative Ileus After Ileostomy Closure: A Systematic Review and Meta-analysis

  • 期刊论文

  • 发表日期：

    2025年5月3日

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  • Jin Ji,
  • Mingrui Jiang,
  • Daorong Wang

摘要

The purpose of this study was to evaluate how postoperative ileus (POI) in patients was affected by ileostomy closure after preoperative bowel stimulation. A randomized controlled trial (RCT) and non-randomized controlled trial (NRCT) were prospectively collected utilizing the PubMed, Cochrane Library, and MEDLINE databases of published research by comparing the stimulation and non-stimulation of ileostomy prior to closure. The study for this meta-statistical analysis was performed in RevMan 5.4, and the best effect model was chosen based on heterogeneity. A total of 293 patients from six retrospective studies (140 in the intervention group and 153 in the control group) were included, as they met the specified criteria. A statistically significant result was in postoperative ileus (MH =  − 0.16; 95% Cl − 0.24, − 0.08; P = 0.002). Preoperative stimulation was associated with early restoration of bowel function. However, Clavien-Dindo complication III, duration of hospital stays, and first passage of flatus did not prove statistically significant. Preoperative bowel stimulation that restores bowel function following ileostomy has a significant impact on postoperative ileus.