Purpose <p>By integrating organizational culture and attention-based view, this paper intends to investigate the impact of organizational culture on compensation structure in biopharma licensing agreements.</p> Methods <p>Generative large language models (<i>GLLMs</i>) is used to infer the implication of management philosophy from organizational culture. Multiple linear regression is used to test the impact of organizational culture on compensation structure.</p> Results <p>Organizational culture significantly influences the compensation structure in biopharma licensing agreements and the level of cash reserve has a moderating effect on the relationship between organizational culture and the percentage of upfront fee.</p> Conclusions <p>A company closer to proactive organizational culture is more likely to conclude a licensing agreement with a higher percentage of upfront fee. In contrast, a company closer to conservative organizational culture is more likely to conclude a licensing agreement with a lower percentage of upfront fee. Moreover, financial pressure compels proactive firms to lean even more heavily toward upfront compensation.</p>