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<p>Healthcare professionals anticipate that nanoparticles will transform therapy monitoring, and this cutting-edge technology is having a significant impact on medication delivery procedures. Additionally, studies have demonstrated the special benefits of using herbal nanoparticles to cure a variety of diseases. Here, we provide a modern Ag NPs green that was formulated by <i>Actinidia polygama</i> to treat thyroid carcinoma. The cytotoxicity and anti-thyroid cancer potentials of the silver nanoparticles/<i>Actinidia polygama</i>-treated cells were checked by the MTT examination for 72 hours on normal and thyroid carcinoma cells, specifically BCPAP, TPC1, K1, and 8505&#xa0;C. Numerous physicochemical ways, including FT-IR, FE-SEM, TEM, EDX, and XRD, were used in this study. When silver nanoparticles/<i>Actinidia polygama</i> were present, the thyroid cancer cell lines viability decreased in a dose-dependent manner. silver nanoparticles/<i>Actinidia polygama</i>’ IC<sub>50</sub> values against the BCPAP, TPC1, K1, and 8505&#xa0;C cell lines were 29, 26, 30, and 32 µg/mL, respectively. silver nanoparticles/<i>Actinidia polygama</i>’ antioxidant potential was assessed through the DPPH. The IC<sub>50</sub> value reported that the silver nanoparticles/<i>Actinidia polygama</i> exhibited notable antioxidant efficacy. Recent nanocomposite technology looks to have anti-thyroid carcinoma potentials due its antioxidant efficacy.</p>

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Green Formulation of Silver Nanoparticles From Actinidia polygama Leaf Aqueous Extract and Evaluating Cytotoxic Activities on BCPAP, TPC1, K1, and 8505 C Thyroid Cancer Cells

  • 期刊论文

  • 发表日期：

    2026年1月6日

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  • Lanling Zou,
  • Qilin Yang

摘要

Healthcare professionals anticipate that nanoparticles will transform therapy monitoring, and this cutting-edge technology is having a significant impact on medication delivery procedures. Additionally, studies have demonstrated the special benefits of using herbal nanoparticles to cure a variety of diseases. Here, we provide a modern Ag NPs green that was formulated by Actinidia polygama to treat thyroid carcinoma. The cytotoxicity and anti-thyroid cancer potentials of the silver nanoparticles/Actinidia polygama-treated cells were checked by the MTT examination for 72 hours on normal and thyroid carcinoma cells, specifically BCPAP, TPC1, K1, and 8505 C. Numerous physicochemical ways, including FT-IR, FE-SEM, TEM, EDX, and XRD, were used in this study. When silver nanoparticles/Actinidia polygama were present, the thyroid cancer cell lines viability decreased in a dose-dependent manner. silver nanoparticles/Actinidia polygama’ IC50 values against the BCPAP, TPC1, K1, and 8505 C cell lines were 29, 26, 30, and 32 µg/mL, respectively. silver nanoparticles/Actinidia polygama’ antioxidant potential was assessed through the DPPH. The IC50 value reported that the silver nanoparticles/Actinidia polygama exhibited notable antioxidant efficacy. Recent nanocomposite technology looks to have anti-thyroid carcinoma potentials due its antioxidant efficacy.