Matrix weights satisfying a Muckenhoupt \(A_p\) -condition relative to a family of anisotropic balls in \({{\mathbb {R}}}^d\) defined by a pseudo-metric are studied. It is shown that such matrix weights satisfy a doubling condition and a reverse Hölder inequality. In the special case, where the pseudo-metric is homogeneous with respect to a one-parameter dilation group, the corresponding Muckenhoupt class is shown to satisfy an invariance property under composition with affine transformations generated by the dilation group. A general sampling theorem is derived for the matrix-weighted space \(L^p(W)\) for Muckenhoupt \(A_p\) weights W along with a corresponding multiplier result for \(L^p(W)\) . An application of the results to the study of anisotropic matrix-weighted Besov spaces is considered.