<p>The dynamics of a gas bubble in a vertical axisymmetric channel filled with fluid is studied experimentally. The aim of the work is to investigate the features of gas bubble rising in a liquid in a channel with a periodically changing profile (sinusoidal) along the axis in the field of gravity and at oscillations of the liquid. The main characteristic in the experiments the average bubble rise velocity. It is shown that in the gravitational field the bubble rise velocity significantly depends on the size and shape of the bubble due to its interaction with the walls of the inhomogeneous cross-section channel and physicochemical properties of the liquid. In the case of the liquid oscillations, the intensity of the gas bubble rise is determined by the amplitude and frequency of the oscillations and differs from the non-vibration case. For both cases, the bubble shape variations and the instantaneous velocity values are experimentally investigated as the bubbles pass through different cross-sections of the channel. For small-sized gas inclusions, a mode of maintenance in a quasi-equilibrium state against the background of oscillations relative to the mean position is found. The experimental results are analyzed and generalized at the plane of control dimensionless parameters: Reynolds, Bond and Weber numbers, drag coefficient. The mechanism of controlling the oscillation and velocity of gas bubble rise by means of a channel of inhomogeneous shape and the presence of fluid oscillations with zero mean flow rate presented in this work is of interest from the point of view of increasing the efficiency of mass transfer processes and heat sink in various technological applications.</p>