In this paper, we introduce and study concepts of mean sensitivity via the Furstenberg family. We present two definitions: \(\mathscr{F}\) -orbit mean sensitivity and \(\mathscr{F}\) -diameter mean sensitivity, for a countable left amenable semigroup S. We demonstrate that a topological dynamical system \(\left( X, \{T_s\}_{s\in S}\right) \) with a transitive point that is not \(\mathscr{F}\) -mean equicontinuous is \(\mathscr{F}\) -orbit mean sensitive. Moreover, if \(\left( X, \{T_s\}_{s \in S}\right) \) is transitive, then it is either \(\mathscr{F}\) -orbit mean sensitive or \(\mathscr{F}\) -almost mean equicontinuous. Furthermore, if \(\left( X, \{T_s\}_{s \in S}\right) \) is a minimal system, then it is either \(\mathscr{F}\) -orbit mean sensitive or \(\mathscr{F}\) -mean equicontinuous. Finally, we show that the definition of \(\mathscr{F}\) -orbit mean sensitivity is preserved under an open factor map.