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<p>This study investigates the dynamic behavior and thermal effects on isolated protein microtubules, which are critical components of the eukaryotic cytoskeleton. By modeling microtubules as beam-like structures, the research develops the governing equations of motion and conducts a comprehensive parametric investigation to assess the influence of shear deformation, temperature variations, and the length-scale parameter on their mechanical behavior. The obtained results are compared with classical models and existing literature, demonstrating that the proposed model—incorporating nonlocal elasticity theory—provides superior precision and aligns closely with experimental data.</p>

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Nonlocal elasticity framework for thermal and mechanical analysis of microtubules in eukaryotic cells

  • 期刊论文

  • 发表日期：

    2025年7月1日

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  • S. R. Mahmoud,
  • Habeeb M. Al-Solami,
  • S. I. Ali,
  • Mohammed Balubaid,
  • A. H. Algarni,
  • Jabr Aljedani,
  • Afaf S. Alwabli,
  • Ghadeer Bukhari,
  • Khalil S. Al-Basyouni

摘要

This study investigates the dynamic behavior and thermal effects on isolated protein microtubules, which are critical components of the eukaryotic cytoskeleton. By modeling microtubules as beam-like structures, the research develops the governing equations of motion and conducts a comprehensive parametric investigation to assess the influence of shear deformation, temperature variations, and the length-scale parameter on their mechanical behavior. The obtained results are compared with classical models and existing literature, demonstrating that the proposed model—incorporating nonlocal elasticity theory—provides superior precision and aligns closely with experimental data.