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<p>In this paper, we designed a pneumatic valve-controlled multi-channel liquid dispensing system tailored for a high-throughput screening platform. During actual dispensing, the system encounters issues such as poor repeatability and deviations from expected dispensing volumes. To address these challenges, we introduced a precision balance as a monitoring tool and developed a fuzzy proportional–integral–derivative (PID) control algorithm to regulate the dispensing process. The precision balance transfers the results of each dispensing quality check to the computer, and the fuzzy PID controller adjusts the dispensing time adaptively, enabling the system to achieve accurate dispensing and ensure repeatability. Our fuzzy PID control system shows excellent control performance with an overall dispensing accuracy of less than 3 % and an overall dispensing repeatability of less than 5 %. This system provides robust support for widespread application in high-throughput screening platforms.</p>

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Design of a pneumatic valve with a fuzzy PID controller for a multi-channel liquid dispensing system

  • 期刊论文

  • 发表日期：

    2025年4月3日

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  • Yan Zhang,
  • Tuanjie Li,
  • Fengfan Zhang,
  • Yuming Ning

摘要

In this paper, we designed a pneumatic valve-controlled multi-channel liquid dispensing system tailored for a high-throughput screening platform. During actual dispensing, the system encounters issues such as poor repeatability and deviations from expected dispensing volumes. To address these challenges, we introduced a precision balance as a monitoring tool and developed a fuzzy proportional–integral–derivative (PID) control algorithm to regulate the dispensing process. The precision balance transfers the results of each dispensing quality check to the computer, and the fuzzy PID controller adjusts the dispensing time adaptively, enabling the system to achieve accurate dispensing and ensure repeatability. Our fuzzy PID control system shows excellent control performance with an overall dispensing accuracy of less than 3 % and an overall dispensing repeatability of less than 5 %. This system provides robust support for widespread application in high-throughput screening platforms.