<p>In this study, an implant-mandibular coupling integral model was constructed. The biomechanical properties of each structure in the implant-mandibular holistic model were explored under dental implant structuring conditions and bone quality. Based on the analysis results of the overall implant-mandibular model, the local area around the implant was studied using the sub-modeling method. By combining the sub-modeling and topology optimization methods, we obtained an efficient and accurate sub-model of four types of bone mandibles; Further, the occlusal conditions of implants for these bone mandibles were numerically simulated, obtaining the optimized structure of implant multi-conditional topology under different bone qualities according to the numerical simulation results; The biomechanical properties of implant topology were evaluated under different bone qualities through the reconstructive design of implant structure to determine optimal distribution of implant materials. The implant sub-modeling analysis is efficient and accurate and can serve as the basis for optimizing implant topology. For the initial reconstructed topology, the primary trend leading to increased stresses in the bone and implant was not optimized. In contrast, for secondary reconstruction topologies with different material removal ratios, the relationship between the influence of the material removal ratio and biomechanical properties of the bone and implant was obtained. The biomechanical performance of the secondary reconstruction topology with a material removal ratio of approximately 20% was superior for all four types of bone mandibles; the better the bone quality, the higher the suitability for the implant topology.</p>