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<p>The current classification of cardiomyopathies (CMP) is based on the recommendations of the European Society of Cardiology (ESC) and follows a&#xa0;holistic patient approach with a&#xa0;major focus on cardiac phenotyping. For the clarification of CMP it is important not only to evaluate the systolic and diastolic function of the heart but also to precisely assess the structure of the myocardium. For structural characterization in the sense of “in vivo pathology”, cardiovascular magnetic resonance (CMR) imaging is used as well as late gadolinium enhancement (LGE)-based detection of disorders of myocardial texture [<CitationRef CitationID="CR1">1</CitationRef>]. Dilated cardiomyopathy (DCM) is a&#xa0;heterogeneous group of cardiac diseases and the clinical course can be highly variable as both genetic (primary) and secondary causes are frequent. A substantial proportion of DCM cases are attributed to an idiopathic origin as the exact origin cannot be designated. The spectrum of secondary forms is large with pathogenetically important metabolic and toxic triggers and also as a result of inflammation and (viral) infections. The main symptoms can be signs of manifest heart failure and also cardiac arrhythmias. As the diagnosis of idiopathic DCM is essentially made by a process of exclusion, the morphological imaging differentiation between ischemic, inflammatory and infiltrative myocardial tissue abnormalities is of essential importance. Finally, in addition to morphological and structural assessments, CMR imaging also enables a prognosis and risk assessment.</p>

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Dilatative Kardiomyopathie – mittels präziser Bildgebung zur Diagnose

  • 期刊论文

  • 发表日期：

    2026年2月17日

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  • Nuriye Akyol,
  • Ali Yilmaz

摘要

The current classification of cardiomyopathies (CMP) is based on the recommendations of the European Society of Cardiology (ESC) and follows a holistic patient approach with a major focus on cardiac phenotyping. For the clarification of CMP it is important not only to evaluate the systolic and diastolic function of the heart but also to precisely assess the structure of the myocardium. For structural characterization in the sense of “in vivo pathology”, cardiovascular magnetic resonance (CMR) imaging is used as well as late gadolinium enhancement (LGE)-based detection of disorders of myocardial texture [1]. Dilated cardiomyopathy (DCM) is a heterogeneous group of cardiac diseases and the clinical course can be highly variable as both genetic (primary) and secondary causes are frequent. A substantial proportion of DCM cases are attributed to an idiopathic origin as the exact origin cannot be designated. The spectrum of secondary forms is large with pathogenetically important metabolic and toxic triggers and also as a result of inflammation and (viral) infections. The main symptoms can be signs of manifest heart failure and also cardiac arrhythmias. As the diagnosis of idiopathic DCM is essentially made by a process of exclusion, the morphological imaging differentiation between ischemic, inflammatory and infiltrative myocardial tissue abnormalities is of essential importance. Finally, in addition to morphological and structural assessments, CMR imaging also enables a prognosis and risk assessment.