<p>Perfectionism is a multidimensional personality construct with both adaptive and maladaptive aspects influencing social functioning. Research using the Perfectionism Social Disconnection Model (PDSM) has predominantly focused on mediation pathways, with no studies examining moderators of the perfectionism-loneliness relationship. Humor styles as interpersonal behavioral patterns may represent theoretically relevant moderators, given their associations with social bonding and cognitive reappraisal. Drawing on the Perfectionism Social Disconnection Model (PSDM), this study examined whether four humor styles moderate the associations between three perfectionism dimensions (standards, order, discrepancy) and social loneliness. Data were collected from a convenience sample of 486 South African undergraduates who completed self-report measures of perfectionism, humor styles, and social loneliness. Hierarchical moderated multiple regression analyses tested 12 interactions between perfectionism dimensions and humor styles. Three significant moderation effects emerged. Affiliative humor moderated the negative order-loneliness association, with the association being stronger at higher levels of affiliative humor. Affiliative humor also moderated the negative standards-loneliness association, with the association being stronger at lower levels. Self-enhancing humor moderated the positive discrepancy-loneliness association, which became nonsignificant at high levels of self-enhancing humor. These findings provide preliminary support for humor styles as interpersonal moderators of perfectionism-loneliness associations, suggesting that the PSDM framework may benefit from considering moderation processes alongside mediation pathways.</p>