<p>This study examines the cultural adaptation and psychometric validation of the ChatGPT Literacy Scale (CLS) for university students in Chile. The CLS, initially developed in South Korea, assesses five key areas: technical proficiency, critical evaluation, critical evidence, communicative proficiency, creative application, and ethical competence. The adaptation process involved two-way translation, content validation by a panel of 12 expert judges, and testing with 620 students from three Chilean universities. Exploratory and confirmatory factor analyses showed that the five-factor structure aligns with the original theoretical model, accounting for 73.5% of the total variance. The high Cronbach's alpha (0.963) and composite reliability (over 0.70) confirm the tool's reliability. Additionally, convergent and discriminant validity were established with AVE values above 0.50 and low correlations between dimensions. Participants rated the instrument as clear and relevant, supporting its usefulness in educational settings. The adapted CLS is a valid and reliable instrument for assessing competencies in the critical and ethical use of ChatGPT, aiding in the development of advanced digital skills and incorporating artificial intelligence into higher education.</p>