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Background <p>Due to its negative consequences, internalized stigma in individuals with severe mental disorders must be addressed and reduced. Aims: This study aimed to evaluate the feasibility, acceptability, and potential effectiveness of a multicomponent pilot intervention designed to reduce internalized stigma. We adopted a two-arm, parallel, single-center, quasi-experimental pilot trial design. The study was conducted at a mental health center in Gran Concepción, Biobío Region, Chile. Thirty-four individuals participated, with 17 in the experimental group and 17 in the control group. The intervention consisted of 10 group sessions, each lasting 90&#xa0;min, administered by professionals from the health center. A quantitative pre-post evaluation was performed, and data were analyzed using an intention-to-treat approach. Additionally, qualitative data were collected before and after the intervention as a secondary component and analyzed using reflective thematic analysis. The recruitment percentage was 51%, the retention rate for those who attended all sessions was 18%, the fidelity of the intervention delivery was 81%, and the acceptability of the intervention was 86%. Recruitment and retention rates did not reach the predefined thresholds for full feasibility, indicating the need for design modifications to support the implementation of a future randomized controlled trial. The intervention was potentially effective in increasing self-esteem.We conclude that a future randomized clinical trial is feasible only if the design can be changed appropriately.&#xa0;Trial registration number: ACTRN12622000919718, Date of registration: 28/06/2022.</p>

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Multicomponent intervention to reduce internalized stigma in people with a diagnosis of severe mental disorder: A mixed pilot trial

  • 期刊论文

  • 发表日期：

    2026年2月17日

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  • Dany Fernández,
  • Pamela Grandón,
  • Claudio Bustos

摘要

Background

Due to its negative consequences, internalized stigma in individuals with severe mental disorders must be addressed and reduced. Aims: This study aimed to evaluate the feasibility, acceptability, and potential effectiveness of a multicomponent pilot intervention designed to reduce internalized stigma. We adopted a two-arm, parallel, single-center, quasi-experimental pilot trial design. The study was conducted at a mental health center in Gran Concepción, Biobío Region, Chile. Thirty-four individuals participated, with 17 in the experimental group and 17 in the control group. The intervention consisted of 10 group sessions, each lasting 90 min, administered by professionals from the health center. A quantitative pre-post evaluation was performed, and data were analyzed using an intention-to-treat approach. Additionally, qualitative data were collected before and after the intervention as a secondary component and analyzed using reflective thematic analysis. The recruitment percentage was 51%, the retention rate for those who attended all sessions was 18%, the fidelity of the intervention delivery was 81%, and the acceptability of the intervention was 86%. Recruitment and retention rates did not reach the predefined thresholds for full feasibility, indicating the need for design modifications to support the implementation of a future randomized controlled trial. The intervention was potentially effective in increasing self-esteem.We conclude that a future randomized clinical trial is feasible only if the design can be changed appropriately. Trial registration number: ACTRN12622000919718, Date of registration: 28/06/2022.