<p>The sense of agency is the feeling of control over one’s actions and, through them, the course of external events. It can be assessed using both implicit measures (i.e., where the experience of agency is inferred from correlates and outcomes of voluntary actions) and explicit measures (i.e., where the experience of agency is inferred from interpretative judgments of being the agent of an action). Among explicit measures, the Sense of Agency Scale (SoAs) has proven to be a valuable tool for investigating general and context-free experience of agency. The aim of this study was to validate an Italian version of the SoAs in a non-clinical sample (<i>n</i> = 301<i>)</i>. Through exploratory and confirmatory factor analyses, we confirmed a two-factor structure (SoPA = Sense of Positive Agency; SoNA = Sense of Negative Agency) of the Italian SoAs, demonstrating good model fits and internal consistency. Additionally, we used network analysis to examine the relationship between the two subscales (SoPA and SoNA) and psychopathological symptoms, including anxiety, depression, obsessive-compulsive traits, and psychotic symptoms. Our findings revealed that the SoPA subscale showed a significant negative association with depressive symptoms, while the SoNA subscale exhibited a significant positive association with obsessive-compulsive and psychotic symptoms. These results indicate that the Italian SoAs demonstrates good validity and reliability, making it a suitable measure for assessing the general experience of agency. Furthermore, its two subscales (SoPA and SoNA) provide valuable insights into the relationship between an impaired sense of agency and psychopathological symptoms.</p>