<p>Homosexuality remains a significant and sensitive topic globally, with its meaning and acceptance varying across cultures and historical periods. In Pakistan, the intersection of cultural norms and religious beliefs heavily shapes societal attitudes toward homosexuality, often perpetuating stigmatization and homophobia. Guided by Social Attribution Theory, this study quantitatively assessed the predictive role of religiosity in attitudes toward homosexuality among young adults. A correlational research design was employed with a sample of 166 participants (111 males, 55 females) aged 18–30 years. Data were collected via the Centrality of Religiosity Scale (CRS), the Klein Sexual Orientation Grid (KSOG), and the Attitudes toward Lesbian and Gay (ATLG) scale. The results revealed a positive relationship between religiosity and homophobic attitudes, suggesting that greater religiosity is correlated with more negative views of homosexuality. Conversely, sexual orientation has a negative relationship with attitudes toward homosexuality. However, mediation analysis showed that sexual orientation did not mediate the relationship between religiosity and homophobic attitudes. These findings highlight the need for culturally sensitive interventions to promote understanding of and empathy toward the LGBTQ + community in highly conservative societies. The study’s multidimensional approach and focus on university students in urban Pakistan provide a novel contribution to existing literature. Implications for policy and education, especially regarding attributional framing and religious discourse, are discussed.</p>