<p>South Africa is home to an estimated 2.9 million migrants, of whom roughly a third are believed to be children. Among these children, the majority are undocumented and reside in the country without the legal documents required for their stay. This paper was aimed at exploring the caregivers’ perspectives on the psychosocial challenges faced by children of deported migrant parents left in Johannesburg. Researchers adopted a qualitative approach and used an exploratory case study design. The population is composed of caregivers who are informally fostering or offering alternative care to children of deported migrants. Twelve (<i>n</i> = 12) female participants who were aged 24–56&#xa0;years were purposively sampled using the registers of beneficiaries that were supported by an international non-governmental organisation (NGO) with social relief packages during the COVID-19 lockdown restrictions. Individual face-to-face semi-structured interviews were employed as the means of data collection, and data were analysed using reflective thematic analysis. The study revealed that migrant children suffer psychosocial challenges such as feelings of anger and frustration, feelings of stress, language barriers, and lack of a sense of belonging, all of which result in behaviour changes. It was deduced from the study findings that children of deported migrants experienced several psychosocial challenges that resulted in poor quality of wellbeing and a low sense of identity. We recommend a holistic approach that integrates focused migration governance, education, and social services to ensure that children left behind by deported migrant parents receive adequate care, protection, and psychosocial support before being assisted to return home and reconnect with their parents. This approach should be central to therapeutic interventions and community services aimed at supporting these children.</p>